Organic Chemistry

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Review: 'What strikes the reader straight away is the way the text is laid out so that it is visually exciting. ...I could go on, so let me end by congratulating the authors and publishers in producing what I am sure will become the standard text in organic chemistry. Perhaps I should just summarise how I felt about the book when I came to put it down: refreshing, exciting and motivational. Tony Barrett, Imperial College London' - '"The authors should be congratulated for compiling a book that should prove very popular with our students...the text is very comprehensive and covers key areas in a very attractive and user friendly way. Thank you to OUP for publishing the book at a really good price". Dr Don Green, University of North London.' - Readership: Major course text suitable for adoption for all mainstream undergraduate organic chemistry courses for use from the beginning/introductory level. Contents 1. What is organic chemistry 2. Organic structures 3. Determining organic structures 4. Structure of molecules 5. Organic reactions 6. Nucleophilic addition to the carbonyl group 7. Delocalization and conjugation 8. Acidity, basicity, and pKa 9. Using organometallic reagents to make C-C bonds 10. Conjugate addition 11. Proton nuclear magnetic resonance 12. Nucleophilic substitution at the carbonyl (C=O) group 13. Equilibria, rates, and mechanisms: summary of mechanistic principles 14. Nucleophilic substitution at C=O with loss of carbonyl oxygen 15. Review of spectroscopic methods 16. Stereochemistry 17. Nucleophilic substitution at saturated carbon 18. Conformational analysis 19. Elimination reactions 20. Electrophilic addition to alkenes 21. Formation and reactions of enols and enolates 22. Electrophilic aromatic substitution 23. Electrophilic alkenes 24. Chemoselectivity: selective reactions and protection 25. Synthesis in action 26. Alkylation of enolates 27. Reactions of enolates with aldehydes and ketones: the aldol reaction 28. Acylation at carbon 29. Conjugate addition of enolates 30. Retrosynthetic analysis 31. Controlling the geometry of double bonds 32. Determination of stereochemistry by spectroscopic methods 33. Stereoselective reactions of cyclic compounds 34. Diastereoselectivity 35. Pericyclic reactions 1: cycloadditions 36. Pericyclic reactions 2: sigmatropic and electrocyclic reactions 37. Rearrangements 38. Fragmentation 39. Radical reactions 40. Synthesis and reactions of carbenes 41. Determining reaction mechanisms 42. Saturated heterocycles and stereoelectronics 43. Aromatic heterocycles 1: structures and reactions 44. Aromatic heterocycles 2: synthesis 45. Asymmetric synthesis 46. Organo-main-group chemistry I: sulfur 47. Organo-main-group chemistry II: boron, silicon, and tin 48. Organometallic chemistry 49. The chemistry of life 50. Mechanisms in biological chemistry 51. Natural products 52. Polymerization 53. Organic chemistry today Index Authors, editors, and contributors Jonathan Clayden, Lecturer in Organic Chemistry, Manchester University, Nick Greeves, Lecturer in Organic Chemistry, Liverpool University, Stuart Warren, Lecturer in Organic Chemistry, and Peter Wothers, Lecturer in Organic Chemistry, both at Cambridge University

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Review: 'What strikes the reader straight away is the way the text is laid out so that it is visually exciting. ...I could go on, so let me end by congratulating the authors and publishers in producing what I am sure will become the standard text in organic chemistry. Perhaps I should just summarise how I felt about the book when I came to put it down: refreshing, exciting and motivational. Tony Barrett, Imperial College London' - '"The authors should be congratulated for compiling a book that should prove very popular with our students...the text is very comprehensive and covers key areas in a very attractive and user friendly way. Thank you to OUP for publishing the book at a really good price". Dr Don Green, University of North London.' - Readership: Major course text suitable for adoption for all mainstream undergraduate organic chemistry courses for use from the beginning/introductory level. Contents 1. What is organic chemistry 2. Organic structures 3. Determining organic structures 4. Structure of molecules 5. Organic reactions 6. Nucleophilic addition to the carbonyl group 7. Delocalization and conjugation 8. Acidity, basicity, and pKa 9. Using organometallic reagents to make C-C bonds 10. Conjugate addition 11. Proton nuclear magnetic resonance 12. Nucleophilic substitution at the carbonyl (C=O) group 13. Equilibria, rates, and mechanisms: summary of mechanistic principles 14. Nucleophilic substitution at C=O with loss of carbonyl oxygen 15. Review of spectroscopic methods 16. Stereochemistry 17. Nucleophilic substitution at saturated carbon 18. Conformational analysis 19. Elimination reactions 20. Electrophilic addition to alkenes 21. Formation and reactions of enols and enolates 22. Electrophilic aromatic substitution 23. Electrophilic alkenes 24. Chemoselectivity: selective reactions and protection 25. Synthesis in action 26. Alkylation of enolates 27. Reactions of enolates with aldehydes and ketones: the aldol reaction 28. Acylation at carbon 29. Conjugate addition of enolates 30. Retrosynthetic analysis 31. Controlling the geometry of double bonds 32. Determination of stereochemistry by spectroscopic methods 33. Stereoselective reactions of cyclic compounds 34. Diastereoselectivity 35. Pericyclic reactions 1: cycloadditions 36. Pericyclic reactions 2: sigmatropic and electrocyclic reactions 37. Rearrangements 38. Fragmentation 39. Radical reactions 40. Synthesis and reactions of carbenes 41. Determining reaction mechanisms 42. Saturated heterocycles and stereoelectronics 43. Aromatic heterocycles 1: structures and reactions 44. Aromatic heterocycles 2: synthesis 45. Asymmetric synthesis 46. Organo-main-group chemistry I: sulfur 47. Organo-main-group chemistry II: boron, silicon, and tin 48. Organometallic chemistry 49. The chemistry of life 50. Mechanisms in biological chemistry 51. Natural products 52. Polymerization 53. Organic chemistry today Index Authors, editors, and contributors Jonathan Clayden, Lecturer in Organic Chemistry, Manchester University, Nick Greeves, Lecturer in Organic Chemistry, Liverpool University, Stuart Warren, Lecturer in Organic Chemistry, and Peter Wothers, Lecturer in Organic Chemistry, both at Cambridge University